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BONE BOOST 

Injecting amniotic fluid from pregnant mums’ wombs ‘CURES agony of osteoporosis and brittle bones’

Injecting cells from a pregnant woman's amniotic fluid can reduce broken bones by up to 78 per cent

MILLIONS of Brits with joint pain and brittle bones could be cured with injections made from the “waters” in the womb.

Scientists found cells gathered from pregnant women’s amniotic fluid can be used to strengthen bones.

Cells from the amniotic fluid of a pregnant mum-to-be could cure agonising joint pain and brittle bones for millions of people, experts discovered
Credit: Getty Images

They reveal injecting these cells can reduce fractures by up to 78 per cent in people with fragile bones.

 

The researchers at University College London carried out early tests in mice and hope to begin clinical trials in humans within the next one to two years.

 

If successful the treatment could help around three million patients in the UK who suffer from bone diseases like osteoporosis and brittle bones.

 

It could also transform the lives of OAPs whose bones have become weak with age, by rejuvenating their skeletons.

 

There are more than 300,000 fractures every year due to fragile bones, mostly in Brits over-50.

 

Experts said the anti-ageing cells can be harvested from women’s amniotic fluid after birth.

 

Dr Pascale Guillot, who led the work at the UCL Great Ormond Street Institute of Child Health, said the therapy could also help speed up the healing of broken bones.

 

She said: “This discovery could have a profound effect on the lives of patients who have fragile bones and could stop a large number of their painful fractures.

 

“As people age, their bones become fragile because the cells responsible for forming new bone become lazy.

 

“We found the stem cells we transplanted release chemical messages that boost the bone forming cells, so they are rejuvenated to make better quality bone again.”

The researchers, whose work is published in the journal Scientific Reports, injected newborn mice suffering from brittle bone disease with human stem cells from the amniotic fluid of pregnant women.

 

They found mice given the stem cells had bones that were stronger and more flexible than those who did not receive the treatment.

This discovery could have a profound effect on the lives of patients who have fragile bones and could stop a large number of their painful fractures

Dr Pascale Guillot ,UCL GreatOrmond Street Institute Of Child Health

The researchers obtained amniotic fluid from women who had undergone a procedure called prenatal diagnosis.

 

This uses a needle to extract a sample of the fluid and carries a small risk of miscarriage.

 

But Dr Guillot said it would be possible to use the fluid when a baby is born and her colleagues have already begun collecting this to save for future use.

 

She said such treatments could also help astronauts, whose bones become weaker after extended trips in space.

 

Osteoporosis occurs when the bones of sufferers become porous, making them weaker.

 

It is most common in older women and is linked to hormonal changes, but it also affects men too.

Scientists found injecting these cells can reduce broken bones by up to 78 per cent
Credit: Getty Images

The diseases is the most common cause of fractures in over-50s.

 

There are also 70 babies each year born in the UK with a condition called osteogenesis imperfecta, or brittle bone disease.

 

These youngsters suffer painful fractures all over their tiny bodies.

 

There is currently no cure for either of these conditions and treating the diseases costs billions of pounds each year.

 

Dr Guillot believes it may be possible to give babies with brittle bone disease these stem cells by injected them into the womb or just after birth, which could help the youngsters develop healthier skeletons.

 

She added: “Some fractures from sports injuries can also be tricky to heal.

 

“The factors released by the stem cells may be able to speed the cells that make bone in a break.”